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Carcinomatous meningitis as a clinical presentation of lung adenocarcinoma – case report

Anna Stanowska1, Barbara Wach1, Izabela Herman-Sucharska2

Affiliation and address for correspondence
Aktualn Neurol 2019, 19 (4), p. 188–192
DOI: 10.15557/AN.2019.0027
Abstract

Carcinomatous meningitis is a rare complication of a malignant disease with a fatal outcome. The greatest predilection for neoplastic meningitis was observed in the course of hematological malignancies, breast cancer, lung cancer, melanoma and gastrointestinal adenocarcinomas. The simultaneous and multilevel nervous system involvement results in the diverse clinical manifestation, therefore it requires a wide differential diagnosis. The diagnosis is based on the correlation of the clinical presentation with the results of additional tests, especially the examination of cerebrospinal fluid and magnetic resonance imaging with contrast. We present the case of 59-year old woman with the carcinomatous meningitis as the first manifestation of lung adenocarcinoma.

Keywords
carcinomatous meningitis, neoplastic meningitis, carcinomatosis, leptomeningeal carcinomatosis, lung adenocarcinoma

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