The specific of sclerosis multiplex (SM) – young patient’s age, heterogeneity of symptoms, not prediction of disease course – inflict that the rehabilitation of persons with SM is one of the most difficult questions of neurological rehabilitation. So the wide spectrum of symptoms in sclerosis multiplex caused that this is chronic disease, which we struggle every day. Sclerosis multiplex is chronic disease of the central nervous system, which occurrence with 30-100 frequency incidents on 100 000 occupants. However, the possession knowledge about this disease, and the possible therapeutic forms can in many cases soften stepping symptoms and have positive effects in many parameters. In last years growth of number scientific reports documenting the effectiveness rehabilitation in sclerosis multiplex was observed. The rehabilitation in multiple sclerosis remains the symptomatic treatment and deals with all the range of motor disturbances caused by this illness (form vegetative to smooth coordination problems). The management of the therapeutic process effectively reduce the disease effects, helping the same pharmacological treatment. Independently of the diagnosis form, the results of SM is self-independently and the lowering quality of life, what make difficult gradually independence, self-service and degree of moving in every conditions. The stabilisation by physiotherapist defects of function and the qualification of proceeding aims, gives the possibility reducing the sizes of occurrence symptoms in measure of disease progress. In this work the authors presents the chosen forms of motive exercises, physical procedures, and some principles of procedures during rehabilitation activities in patient’s with SM.