Spinal pain syndrome and headache as initial manifestation of spinal cord tumour – a report of two cases
Katedra i Zakład Patomorfologii (Ewa Iżycka-Świeszewska) 
Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii (Joanna Stefanowicz, Anna Szołkiewicz, Elżbieta Drożyńska, Ewa Bień, Katarzyna Połczyńska, Agata Maciejewska, Anna Balcerska) 
Klinika Onkologii i Radioterapii (Ewa Szutowicz-Zielińska) 
Correspondence to: Akademia Medyczna w Gdańsku, ul. M. Curie-Skłodowskiej 3a, 80-210 Gdańsk, tel.: 058 349 21 72
Aktualn Neurol 2007, 7 (2), p. 127-131

Two cases of intraspinal thoracolumbar tumours with meningeal involvement in boys aged 10.5 and 12 years are presented. Medical history of both patients comprised headaches and back pains lasting for some weeks and months before admission. Because of the significant extension of the neoplastic process, one patient was disqualified from tumour resection and was administered with neoadjuvant chemotherapy. The second patient received partial tumour resection and supplementary intense chemotherapy. Both children died of disease progression after 2 and 15 months after first symptoms occurrence, respectively. Autopsy revealed malignant gliomas with extensive meningeal involvement as well as neoplasm dissemination within central nervous system via cerebro-spinal fluid in both cases. Vertebral pain is a rare neurological symptom in children, requiring particular attention and thorough radiological examination. It needs to be stressed that headaches may be also the first symptom of the tumour located within vertebral column. 

Keywords: vertebral pain, spinal cord tumours, malignant gliomas, children